I lived in Phoenix for a few years. The only thing I did differently was thicker oil in my 2004 GTO. I drove it hard when I wanted to and I didn't like seeing oil pressure drop below 20 psi at idle, which I would get occasionally when hot. I even ran Mobil 1 15w50 in it a couple of times, though that was obviously unnecessary and usually ran 0w40 instead. If you aren't a ham fisted hooligan like me, I don't think you'd do anything to see anything unusual out of a car driven normally with a cooling system in good condition.The 5 million people that live there and drive there on a daily basis cant be wrong with following the owners manual. I-10 out of Blythe has a long climb which can stress your cooling system. Its about 10 miles long and 75MPH speed limit. Confirm your fans are working and top off coolant.