I decided to give it a go in my Gladiator, which I purchased with 35k miles. I ran Mobil 1 EP, mostly, with a couple runs of ESP. So I am running at least one, maybe two, 5k OCI's with R&P. I am not sure there is much in there to clean, but if there is, a couple OCI's should take care of it. Then I'm back to Mobil 1 Advanced Clean or ESP, whichever I decide to run.
I may run it in my Wrangler, too. But it's had Mobil 1 ESP in it from new, so again, not sure there is much to clean. It has 116k on it now.
I also might do an OCI or two in my Vette, which I picked up at 58k miles. It's now got 72k. Again, I don't think it can hurt.
The evidence is pretty clear that VRP works.
My only concern is if they had to change the formulation due to effects from the fight with Iran.