Personally, I think on a high mileage car it will take quite a while to see any benefits.
Before I started using FP, the porcelain around the center electrodes was always covered in black soot and my injectors always leaked down when the car sat for more than 12 hours.
After 5 - 7 treated tankfuls of gas (several of them at 2-3oz/5gal, a couple untreated,the rest at the normal 1oz/5 gal) the plugs now have gray porcelains and the car fires right up even after sitting all weekend (no injector leakdown).
I hadn't yet seen any fuel mileage change before cold weather showed up, since I started using FP in July and only fill up twice/month. However, my winter gas mileage is up from last year, 22-23mpg last winter vs. 24mpg this year. Maybe because of warmer weather? I don't know, but I don't get the 2-3 mpg variation from tank-to-tank like I used to. Maybe this is mostly from the cleaner injectors?
Next time I pull the plugs I will have to have another look at the piston crowns; I used to be able to see carbon buildup on them through the plug holes... would be interesting to see if they have cleaned up any.
My wife's 2001 Civic didn't show any improvement with FP, don't know yet about the new Accord she replaced it with. we are only on it's second tank of gas, the first to be treated with FP. Last tank was 23mpg (<500 mi on engine at fillup).