Nice!
I have a 2008 E320 w/163k miles. Same V6. I'm running Mobil 1 ESP 0W-30 with 5k oil changes. It's spotless inside. Factory was Fuchs, that and I also used Pentosin until the Mobil 1 ESP became easy to get. Still only $28/5qt at Walmart. The MLs run hotter from what I read, so if you're not comfortable with the 30, there are several xW-40 that are 229.51 and 229.52 approved, including some Mobil. Mobil 1 ESP is now the best bang for the buck purchased at Walmart. You won't find anything better except perhaps HPL xW-30 Euro.
Don't go to an HDEO. There is no better protection for the engine than the approved 229.52 oils. Heed MB. Ignore Bubba and his cousin who knew a guy.
Afternote, check your motor mounts. They tend to get leaky with age and collapse. The SUV will feel much smoother with good ones.