I remember back then there was some problem for people with 50Mhz FSB vs 66MHz FSB on the IO. Some IO works fine with 50MHz as is but the 66MHz FSB one has to step down to 33MHz, or was it the other way around they were ok at 33MHz but not at 50MHz.
In theory as long as you get your multiplier and bus correctly it should run, in the worst case slower.
Back then the CPUs weren't as picky about micro code, just as long as you have the clock speed correct it "should" boot. Everything was jumpered so you can calculate back and forth to see what is wrong.