No. Handgun personal carry permits are rarely, rarely issued. One could technically apply, but it would never fly. Heck, when you apply for a restricted weapons permit (i.e. handguns, various military type firearms), you have to provide a reason for acquiring such firearms. Collecting and target shooting will get you approved. Personal defence, particularly against animals, will get you shot down, as it were, in short order. Heck, with the storage regulations on handguns, you're not going to be having a handgun at easy access, loaded, near the front door to carry out with you to take the trash out.
You can get a good carbine, particularly a nice lever action, in darn near any caliber you want. That would be my first choice, anyhow, since at least it's good for several things.
I don't think very large caliber handguns sell too well up here. Aside from collectors, anyone else will be simply using it at the range to punish their hand and their wallets, since that's the only legal place to use the thing.
I think a Freedom Arms revolver in .454 Casull would be a lovely firearm to experience, but has no real practicality. Unless you get accosted by a grizzly when you're at the target range, you're pretty much out of luck with respect to using it to defend yourself. And, I suspect a couple hours of shooting it for target practice could get expensive and painful.