Vitamin D

I was just surprised how well it did given my labs for the past 15 years. My hematocrit creeps up and I donate blood to get it back down. It was able to project % drop from a donation. Distinguish between the likely cause being a medication vs age. It looked at ferritin levels and other lab markers and recommended labs after every 3rd donation which was absolutely appropriate. The best part was it explains its rationale and it was spot on. If I just asked what causes hematocrit to go up I'd get a general answer. Give it actual data and it gave me an answer specific for my situation.

I was at an oral pathology lecture recently, all the clinical photos were from the presenter and not on the web. I was having fun taking pictures of slides and ChatGPT got the diagnosis correct on the first attempt about 90% of the time and the correct diagnosis was in the top 3 differential 100% of the time over about 50 slides. Some of these slides didn't show enough anatomical landmarks to even be sure what part of the body you were looking at and it still got them correct. As an example, this was carcinoma in situ caused by HPV-16 and it nailed it with just the picture. View attachment 326902
Maybe it already had that same exact picture with the diagnosis while training.
 
Why don't you guys get Vitamin D the natural way by exposing yourselves to sunlight?
I've asked a few people the same question. Their answers were the same, I don't want to get skin cancer. And if you slather yourself up with sun screen, you might as well be wearing a jacket, hat, and pants. Which one guy I know does. I take Vitamin D year round, as the medicine I take has a side effect of depleting Vitamin D from my body. I still like being outside in the summer, and I don't get fully dressed when outside, But in the winter, there's not much chance of getting enough Vitamin D anyway.,,
 
Why don't you guys get Vitamin D the natural way by exposing yourselves to sunlight?

There is very little sunshine up here in the winter months and even when there is, the UV index is very low in the winter months. I would have to be outside for the entire day just to get the same amount of Vitamin D that I can get in a half hour in the summer.

Because of my job as a tour guide, I’m outside all day long from May until the late fall, so I get a huge amount of natural Vitamin D then.
 
In Sweden and other Nordic countries, they use sunbeds during the winter months for vitamin D.

Off topic, I hope sanity returns to our medical establishment about UV exposure and cancer. We have this madness where NIH research papers say the sun doesn't cause melanoma (or lack of sun causes melanoma), and the cancer and dermatology medical associations push heliophobia.
 
last year, my GP told me I was Vit, D deficient, and that I had too much Potassium. ( had been taking a Potassium Citrate, mainly for the Citrate, as the Urologist said my Citrate level was low. Citrate and Potassium both help get excess sodium out of your system, and I had had some Kidney stones, that were largely sodium)

anyway, back to the Vit. D... the GP told me to take 3000 IU daily, Head to the store... available in 1000, 5000, and 10000 IU. I went Middle of the road, Got the 5k IU, and take it every other day. at the next visit, he asked if i was taking the Vit. D, told him the i was taking 5k every other day, he was happy with that arraignment.
 
It was mentioned in Ekberg's video, but it's worth restating that processing of Vitamin D increases your body’s demand for magnesium. If you're taking large doses of Vitamin D, you may find yourself in magnesium deficiency, so you should combine Vitamin D supplements with magnesium supplements if you don't get enough from your diet.

If you're magnesium deficient, not only will your body be unable to absorb all that Vitamin D you're taking, you will also be more susceptible to muscle cramps, twitching, fatigue, irritability, anxiety, etc.
 
https://www.mayoclinicproceedings.org/article/S0025-6196(15)00244-X/fulltext

It's almost impossible to OD on Vitamin D unless you really work at it.
The issue back in ye olde times was 2 fold.

Very old sources had a megadose of normal A and D together

Typically the type of both along with other things that might be in the supplement likely included synthetic and suboptimal mixes, even the notorious “timed release “ versions.

Generally unless you are very low, you should alternate A and D and avoid timed release and synthetic versions.

The most safe option is to avoid old fashioned vitamin A and use a cartinoid like beta carateen.

Remembering many people do not absorb a or d very well making old assumptions moot.

Correllation is not causation, doctors made that mistake conflating the things I mentioned as also being an issue with natural sources.

Doctors have held this misconception 70+ years so it takes a long while to change attitudes.

Taking different types of a snd d, even synthetic in a broad spectrum way isn’t bad if you are low but d2 and A need to be limited because they are used differently in the body and more likely to have side effects.
 
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