Let's say you were a Type I diabetic and you had to go to the hospital twice a week to have blood dialysis work done,due to renal failure of the kidneys.Would you want to keep the membrane filter intact from the first visit that week or would you change it? Just like they say,"Oil is the life blood of an engine." Same as blood,it's filtered through the kidneys,so with the dialysis machine the membrane is the filter,acting as the kidneys.