250k miles is what I consider high, anything under 100k miles is still a virgin waiting to be discovered. From 100k to 150k is where build quality will be determined. Reasonable maintenance will take most vehicles built well past up to 200k miles. Good maintenance will take it to 200k miles and now we're dealing with a potential bullet proof design here. This is a good time to look for a same vehicle that has a good body and be ready to cherry pick parts for your iron horse.
Most Acura, especially the Integra and Legend, can easily get pass 300k miles if not abused. A Cherokee can do the same if people just change the oil and ATF on it. A Civic, if not abused, can get to 400k miles. Same goes for Accord.
On the other hand, many Toyota are mechanically tough but their body construction is rather shoddy and become very unpleasant to drive pass the 15 years mark. My 92 Corolla bounces a lot on bump and curve while the family 88 Integra is still structurally sound.
I have seen very hit or miss with Ford trucks. I notice some will go forever while others, even the high end F350, needing engine and transmission rebuild under 150k miles while the body is still in excellent shape and look great. I wonder if it was the build quality or how the owner use it. This is what scares me away from things classified as work truck; some are great but many are simply abused and neglected because they are operated by idiots.