Does the Echo have a catalytic muffler? If so, I would probably stick to 50:1 for it, though I doubt 45:1 would do serious damage.
I sometimes mix up a batch somewhere between 40:1 and 50:1 to use in everything, sometimes I buy engineered fuel, sometimes I mix different grades of engineered fuel if I'm running low, and a couple times I've mixed it in the equipment's gas tank. I go through a fair amount of 2 stroke gas though and the four engines I have that use it are kind of cheap/free stuff I don't care that much about. That said, I've never had a fuel/oil related problem with my 2 strokes.