The Mystik 15w50 is designed for older agricultural equipment. By older, I mean pre-Tier equipment, so from the 1940’s to the 1990’s.
Will it work in a 2003 ISX? Yes. Would I personally recommend it? Not really. If you’re losing a lot of oil pressure, you’re going to have something mechanical going on. I would start with that instead of throwing a (fairly) expensive oil at the problem.
But to answer the question, it’s a good oil. Certainly has a niche in the market place.
My fleet still has a few 1980’s to 2007 engines out there. (Mostly CATs) and we run all 15w40’s in them.