I don't think we have any "big snake" or python problems around me yet. Louisiana. But I have seen water snakes in the swamps when hunting years ago that shocked me they were so big. I once hunted, fished and trapped all thru swamps and wet lands all across south central La and could not even find an alligator if I wanted to.
This all changed around 2005-2006 and ever since. Many (too many) of the older generation of swamp men I once knew have all retired and died off. So , since then , over time there are very few trappers or alligator hunters in the area to take the place of those men.
What has happened over the last near 20 years is an explosion of the alligator population. There is near no place around , swamps or woodlands, canals and rivers near me now that one can not run across all size alligators. Many can be seen dead after being hit by vehicles on interstates and highways that pass thru the lower swamp land areas. They come out and travel thru any source of water at night from rivers, canals to ditches etc.... I can't get out there anymore. Do not have my boats and can not venture into the swamps these days like I once could but I been told by guys who still fish and hunt some of the areas that they are full of alligators these days. They have not many real predators anymore.
One thing good has come out of it. The alligators have pretty much eliminated a once big problem we had with a swamp eating animal similar and along with beavers.... nutrias which are very large vegitation eating animals that not only killed grass lands but also dug up the ground anywhere they went. The alligators seem to have the beaver and nutria populations under control as they prey on them easily.