You know Ford started doing OHC engines in the 60's right? The Ford Indy Cammer was probably the earliest example, then there was the 427 SOHC. The whole modular family (which the current Coyote engine is a member of) can't be an "exception", as it it simply soundly torpedoes the theory. Ford also made the excellent Duratec family of OHC engines which were both V6 and i4 (though a few were Mazda derived).
Chrysler's 4.7L wasn't awful, but was prone to some issues that had nothing to do with it being OHC.
Euro marques have had notable issues with OHC vee engines. BMW's M62 was somewhat notorious for timing chain issues, as was Audi's 4.2L V8.
The VAG EA888 (an i4) was the target of a class-action lawsuit for timing component related failures.
Honda's V6 with cylinder deactivation has been quite problem-prone with oil consumption and sludge/varnish.
I'm not up on my GM history, but I'm sure they have produced several successful OHC engines along with the black eyes like the early Northstar ones.
Ultimately, they've all produced some turds, doesn't matter whether they are OHC or OHV.