Skirt length, ring placement, bearing wear, and geometries in the design I'd be guessing.
But, I'd never run a nitrile ADBV Fram on a slapping engine.
As gfh777 mentioned, go for a Wix or NAPA Gold (same thing), but more as a precaution and feel-good measure.
Mix it up, get different high-quality filters, and each OCI try a different one. Again, probably won't help, but at least you are trying something.
For oil, I'd run German Castrol 0W30 and see if it helps. If not, I'd run a 0W40 for a short OCI and see if it helps. Plan to dump it in a few hundred miles if you worry about oil pressures and lubrication. This is purely to "rule out" lubrication as the factor.
If none of this helps, I'd stick to Pennzoil Yellow Bottle 5W30 and keep the OCI 5000 miles with a Wix filter to clear out the aluminum and elevated iron out of the sump.
I have seen the pistons of a bright and clean engine (would lead me to believe it was using syn) that had massive slap.
The aluminum skirt was pounded on the leading edge as if someone took a framing hammer and lightly tapped up and down it a few hundred times. And the aluminum looked smeared and scuffed.
From the visual evidence, and looking down the cylinder wall where the skirt was damaged, I didn't see any harm to the cylinder and the measurements fell into spec with a t-gauge.
I don't want to talk out of my rear for too long, but if it is cringe-worthy and a known engine trait (engineering), just play with oils and filters and see it as the nature of your beast, like a beloved spouse that isn't perfect but you wouldn't trade for anything.
Edit: Just read your mileage. Get a thick dino up to 40wt and call it a day.