My personal rule has been no more than 50,000 on a set of regular plugs.
Now on my last Accord i changed the Iridiums at 100,000 miles by recomendation (they were still perfoming fine.. The 07 Accord has 90,000 and still has the factory plugs in it (and is still sharp as a tack) with no problems. Same with my Silverado, its got 75,xxx on the clock with the factory Iridiums in it.. Its been recomended by my shops to swap them at 100,000 and im sure i will.. im just curious what everyone else is doing.