The only time I have been able to verify a difference in fuel consumption, attributable to oil used, was in a single engine aircraft. In that case, fuel use is measured in gallons per hour, at a given power setting (RPM X Manifold pressure).
Using Mobil I aircraft oil, we got a solid 2% better consumption, over conventional shell multigrade. I suspect the difference was from better ring sealing, because their was also considerably less oil consumption. With the combination of less fuel and less oil consumed, the higher priced synthetic actually paid for itself over an OCI.
Unfortunately, Mobil had to recall that oil, because it did not effectively remove the lead from AV gas from the piston and rings. (This was not a concern for our application, since we were using Mogas (Standard unleaded gas).
In a wheeled vehicle, unless you are checking records for the entire length of an OCI, it is impossible to duplicate conditions exactly. And.......I would doubt that any oil would give more than a 3% difference......