Old 96 F250 back in 2007, removed the bed to install a goose neck hitch, and airbags. On a sloped drive way, alone, using a cherry picker engine hoist. And 4 harbor freight yellow straps. Beds are not very heavy.
I wound never remove a full tank, nor do it under a pickup bed, that so easy comes off. Align bolt holes? You can easily slide it or even pick up one corner.