2007 Tacoma with almost 232,000 miles here. Bought new in 2007, so I know its history.
Engine and transmission - rock-solid. I'd rely on them to drive from here to Seattle. And I've replaced all the wheel bearings and rebuilt the driveshaft. Suspension components are original, but there's nothing to lead me to believe any of it needs replaced. Steering feels great, and the truck tracks dead-straight, and, of course, it's lived its whole life in the South. The miles are mostly highway.
We take our trips in the wife's 2018 Civic, but, I guess what I'd worry about if I were to take the Tacoma on a long trip would be a failure of the starter, alternator, fuel pump, or water pump, since they're all original components. No indication that any of those critical components are on their way out, but, I've seen those things fail on vehicles with far fewer miles.
Starter or alternator would be pretty easy to source and replace. The other 2, I haven't looked into how hard they are to get to or anything.
What sucks is that my truck has been hit at least 4 times in parking lots. The latest incident happened just a couple of days ago. It's extremely discouraging when you do your level best to take great care of a vehicle, washing, waxing, detailing, doing all the maintenance it needs in order to go the distance and get your money's worth out of it, and then some lowlife damages it in a parking lot and doesn't have the class to leave a note or anything. Wish I had a dash cam in my truck. Might not have caught what happened, but, then again, it might have.