buster, you can go from SFO north on 101 to SF, take I-80 to Sacramento, then take 50 to Tahoe. You can also go from SFO across the Bay via 92, then take 580 (you'll pass hundreds of windmills) towards Livermore, take 205 in Midway, then take I-5 to Sacramento, then take 50. In either case, it's really scenic only once you hit the Sierra foothills.