Here is how to save it:
If it is a tube with a screw cap, put the cap over the nozzle and completely fill the cap with silicone, then screw it on. It is not too tuff to get off next time you need it and only the stuff in the cap will harden, the tube contents will be fine.
If it has a push on cap, like a caulking tube, I throw out the cap, put a glob of silicone on a medium duty plastic film then push the nozzle into the glob and wrap it up while removing all the air you can, secure with rubber band or the like.
You can also save paint rollers for a second coat later by wrapping them in plastic, that way they do not dry out and you can use them hours later, even the next day. I use plastic shopping bags, just watch out for holes, must be air tight.