What kind of difference are you looking for?once the fuel system is clean and there are no deposits on the intake valves i cant imagine there would be any difference at all other than the keeping it that way,thats a good thing.IMO you are taking the correct approach to keep the engine running at its best rather than letting it get dirty then cleaning it up.Todays gasoline at least in the north east where i live are not very good at even keeping the engine running properly never mind keeping deposits under control,this product as well as a few other quality products of this type definitely help to not only keep the fuel system clean but to keep the in tank fuel sender in good working order,an issue that has arisen more and more since the introduction of the mandatory 10% ethanol mix.To replace this unit most of the time requires removing the fuel tank and sometimes is integral with the pump which can cost a few hundred $$,preventing this is well worth the price of the small amount you mention but you wont "feel" the difference.