I have owned a few high mileage vehicles, most notably three 91 Corolla sedans at different times.
1st one: Auto, purchased new by my parents, totalled by some idiot at 182k.
2nd one: manual, purchased at 184k, sold at 200k.
3rd one: manual, purchased at 150k, still own at 180k.
All three were/are great cars. One can get away with the bare minimum on maintenance with them, although I take very good care of mine. They aren't perfect cars, but are certainly some of the best on the road. My current one should reach 300k with ease, though I drive it only rarely.
Other high mileage cars.
1990 Mazda MPV 2.6L, 0-155k. Lot's of repairs, tranny failure finally did it in.
1996 Toyota Camry 5S-FE, 139k-151k currently. Runs great, despite previous owner's abuse. Some issues that need to be taken care of, but not pressing.
Next car I'm going to get is a 1990s Ranger or B-Series. I hope I have equal success with that truck.