There are two commonly used ways to fasten wheels to a hub: lug-centric and hub-centric. Learn how to tell them apart.
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Look at the pic for the hub centered wheel and note the red arrow and NO GAP. The contact made there is what keeps the wheel centered. The poster Surestick wants anti seize applied to just that circle of contact. That contact area is as wide as the thickness of the rim there which is no more than a quarter inch.
Interesting thesis put forward by Surestick, never come across it before. Not sure how valid the reasoning is, whether the lug studs are designed to take the shear forces or not.