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Another quick opinion....
If you buy new, buy Japanese, if buy used, by American..
My advice is ...
If you buy new buy Japanese (company... the car is fine even if designed in California and made in Tennessee).
If you buy slightly used (
If you buy very used (>7 years) buy Japanese. They are not falling apart at that age, and have plenty left.
If you buy very very used buy something German and really fancy. Something that was outrageously expensive to begin with but has obviously been babied. Enjoy.
My biases are pretty clear. I drive an 18 year old Porsche (summer), a 13 year old Mazda (winter) and a 6 month old Mazda (6 month old baby).
Back to the original question. I would not limit my car buying based on one criterion of engine design. You eliminate a lot of really great cars that way. If we added up the list of potential maintenance issues we would rule out every car.
You do want to be cognizant of the issues and particulars of each car. On two relatively expensive used cars with interference engines the first thing i did upon buying was replace the timing belt and water pump as a defensive measure. These were situations where $300 worth of parts and 4 or 5 hours worth of labor were worth the peace of mind.
On some cars the belt tension needs to be monitored and adjusted as necessary so it definitely is a preventative maintenance issue. I hear some people prefer timing chain designs because of this but I think each has its own issues.