Motorcycles used CV (constant velocity) carbs for years and I believe there are still a few models that may have them (Suzuki DR650 for example). They have a variable venturi and do provide better control over the air/fuel ratio than conventional fixed diameter venturi carbs.
I don't know that I noticed any massive gain in MPG with them. I did notice a decrease in throttle response when compared to a conventional carb. We would try all sorts of tricks to make the vacuum operated slide (variable venturi) pull up or open faster.
These carbs did not work well for hard core dirt bike riding, such as a dual sport bike ridden on a motocross track, as the slide's weight would 'close' the carb when landing from a jump. Causing the engine to lose power just when needed and when traction was highest.
I converted my KLR600 from a Mikuni CV carb to a conventional Del'Orto pumper carb of the same size. The difference was remarkable. The variable venturi carb was not ideal for good performance.
Back in college, I had a '66 Mustang with downdraft Weber carbs. They worked really well with stunningly great throttle response, they would ice up though. MPG was acceptable, and peak power was on par with a single plane intake manifold and big Holley carb, with much better low end and no bogging. Today, the setup is again popular, and my old college roommate's brand new 347 cubic inch Ford small block makes a solid 550+HP.
EDIT: I guess my point is that such carb setups can be designed to provide even fuel distribution for each cylinder. And/or can be designed to provide excellent atomization. 2 strokes often use very crude carbs with great results. The air/fuel movement through reed valves, around the hot crankshaft, and through hot transfer ports helps with atomization.