Now, with newer engines, I think some auto manufacturers are using the plugs to gather individual cylinder data to tailer injector pulse/timing and individual advance. Not exactly sure how the sensing function works (I think Jacobs holds some of the patents on it) but I have heard it is important to use the OEM plug.
This^^^
They use the plug to sense the combustion health -- IDK if it reads miniscule voltages present during the burn or if it looks at how the spark breaks down once flame is achieved, but it does read. Probably some high freq resonance characteristics of certain plugs could conflict with how the ecu reads that signal.
I do not think wasted spark systems have this intelligence, but 1-1 COP systems can.