While I would prefer to run conventional grade gasoline in my 2 cycle engines, the reformulated blend with ethanol gas, required in the southeastern Wisconsin counties, works OK.
The only problem appears to be storage related, as oxygenated gasolines are reported to form gums quickly. This leads to carburetor problems & more cylinder deposits.
A good practice is to only mix a gallon or less of 2 cycle gas/oil & use it up within 30 days to avoid the storage problems.