Marijuana has been mainstream in America since the 1960's and was underground since the early 1900's.
While controversial, medicinal use is legal in 28 states, DC, Guam and Puerto Rico. About half the states have legalized recreational use.
The most common conditions accepted by states that allow medicinal cannabis relate to relief of the symptoms of cancer, glaucoma, human immunodeficiency virus/acquired immunodeficiency syndrome, and MS.
Today, I believe Israel is the leader in marijuana studies. There are more than 110 clinical trials involving cannabis are underway, more than any other country.
The US Medical Marijuana and Cannabidiol Research Expansion Act became effective in Dec 2022.
Don't get me wrong, I am the last one to recommend any recreational drug use, but pot has been around for a long time. Naysayers have been demonizing the devil weed forever, but it seems to be the least of the many evils. And it certainly appears to have helped a lot of very sick people. Perhaps you've heard the "Charlotte's Web" story.