Roundup/Glyphosate probably safe after all

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http://www.reuters.com/investigates/special-report/glyphosate-cancer-data/
Quote:
When Aaron Blair sat down to chair a week-long meeting of 17 specialists at the International Agency for Research on Cancer in France in March 2015, there was something he wasn’t telling them.

The epidemiologist from the U.S. National Cancer Institute had seen important unpublished scientific data relating directly to a key question the IARC specialists were about to consider: Whether research shows that the weedkiller glyphosate, a key ingredient in Monsanto’s best-selling RoundUp brand, causes cancer.

Previously unreported court documents reviewed by Reuters from an ongoing U.S. legal case against Monsanto show that Blair knew the unpublished research found no evidence of a link between glyphosate and cancer. In a sworn deposition given in March this year in connection with the case, Blair also said the data would have altered IARC’s analysis. He said it would have made it less likely that glyphosate would meet the agency’s criteria for being classed as “probably carcinogenic.”

But IARC, a semi-autonomous part of the World Health Organization, never got to consider the data. The agency’s rules on assessing substances for carcinogenicity say it can consider only published research – and this new data, which came from a large American study on which Blair was a senior researcher, had not been published.


also http://www.motherjones.com/environment/2017/06/monsanto-roundup-glyphosate-cancer-who/
 
It's safety has been widely known for maybe 30 years?

I guess the political will to acknowledge facts is a different matter...
 
Remember when DuPont were sponsoring research that proved no Ozone damage...

right until the point that it suited their purpose to have it phased out.
 
It appears that the weed killer we use on our lawn is more cancerous than roundup. Too bad I can't just use roundup on the lawn.

However, just because roundup isn't cancerous does not mean it is safe. There are other diseases that can be caused by pesticides. While the science is not yet "mature" on these risks, the jury is still out on some of these risks...

ADHD: In farming communities, there’s a strong correlation between Roundup exposure and attention deficit disorder (ADHD), likely due to glyphosate’s capacity to disrupt thyroid hormone functions.

Alzheimer’s disease: In the lab, Roundup causes the same type of oxidative stress and neural cell death observed in Alzheimer’s disease. And it affects CaMKII, an enzyme whose dysregulation has also been linked to the disease.

Anencephaly (birth defect): An investigation into neural tube defects among babies born to women living within 1,000 meters of pesticide applications showed an association for glyphosate with anencephaly, the absence of a major portion of the brain, skull and scalp that forms during embryonic development.

Autism: Glyphosate has a number of known biological effects that align with the known pathologies associated with autism. One of these parallels is the gut dysbiosis observed in autistic children and the toxicity of glyphosate to beneficial bacteria that suppress pathogenic bacteria, along with pathogenic bacteria’s high resistance to glyphosate. In addition, glyphosate’s capacity to promote aluminum accumulation in the brain may make it the principal cause of autism in the U.S.

Birth defects: Roundup and glyphosate can disrupt the Vitamin A (retinoic acid) signaling pathway, which is crucial for normal fetal development. The babies of women living within one kilometer of fields sprayed with glyphosate were more than twice as likely to have birth defects according to a study from Paraguay. Congenital defects quadrupled in the decade after Roundup Ready crops arrived in Chaco, a province in Argentina where glyphosate is used roughly eight to ten times more per acre than in the U.S. A study of one farming family in the U.S. documented elevated levels of glyphosate and birth defects in the children, including an imperforate ****, growth hormone deficiency, hypospadias (an abnormally placed urinary hole), a heart defect and a micro [censored].

Celiac disease and gluten intolerance: Fish exposed to glyphosate develop digestive problems that are reminiscent of celiac disease. There are parallels between the characteristics of celiac disease and the known effects of glyphosate. These include imbalances in gut bacteria, impairment in enzymes involved with detoxifying environmental toxins, mineral deficiencies and amino acid depletion.

Chronic kidney disease: Increases in the use of glyphosate may explain the recent surge in kidney failure among agricultural workers in Central America, Sri Lanka and India. Scientists have concluded, “Although glyphosate alone does not cause an epidemic of chronic kidney disease, it seems to have acquired the ability to destroy the renal tissues of thousands of farmers when it forms complexes with [hard water] and nephrotoxic metals.”

Colitis: The toxicity of glyphosate to beneficial bacteria that suppress clostridia, along with clostridia’s high resistance to glyphosate, could be a significant predisposing factor in the overgrowth of clostridia. Overgrowth of clostridia, specifically C. difficile, is a well-established causal factor in colitis.

Depression: Glyphosate disrupts chemical processes that impact the production of serotonin, an important neurotransmitter that regulates mood, appetite and sleep. Serotonin impairment has been linked to depression.

Diabetes: Low levels of testosterone are a risk factor for Type 2 diabetes. Rats fed environmentally relevant doses of Roundup over a period of 30 days spanning the onset of puberty had reduced testosterone production sufficient to alter testicular cell morphology and to delay the onset of puberty.

Heart disease: Glyphosate can disrupt the body’s enzymes, causing lysosomal dysfunction, a major factor in cardiovascular disease and heart failure.

Hypothyroidism: House-to-house surveys of 65,000 people in farming communities in Argentina where Roundup is used, known there as the fumigated towns, found higher rates of hypothyroidism.

Inflammatory Bowl Disease (“Leaky Gut Syndrome”): Glyphosate can induce severe tryptophan deficiency, which can lead to an extreme inflammatory bowel disease that severely impairs the ability to absorb nutrients through the gut, due to inflammation, bleeding and diarrhea.

Liver disease: Very low doses of Roundup can disrupt human liver cell function, according to a 2009 study published in Toxicology.

Lou Gehrig’s Disease (ALS): Sulfate deficiency in the brain has been associated with Amyotrophic Lateral Sclerosis (ALS). Glyphosatedisrupts sulfate transport from the gut to the liver, and may lead over time to severe sulfate deficiency throughout all the tissues, including the brain.

Multiple Sclerosis (MS): An increased incidence of inflammatory bowel disease (IBS) has been found in association with MS. Glyphosatemay be a causal factor. The hypothesis is that glyphosate-induced IBS causes gut bacteria to leak into the vasculature, triggering an immune reaction and consequently an autoimmune disorder resulting in destruction of the myelin sheath.

Parkinson’s disease: The brain-damaging effects of herbicides have been recognized as the main environmental factor associated with neurodegenerative disorders, including Parkinson's disease. The onset of Parkinson’s following exposure to glyphosate has been welldocumented and lab studies show that glyphosate induces the cell death characteristic of the disease.

Pregnancy problems (infertility, miscarriages, stillbirths): Glyphosate is toxic to human placental cells, which, scientists say, explains the pregnancy problems of agricultural workers exposed to the herbicide.

Obesity: An experiment involving the transfer of a strain of endotoxin-producing bacteria from the gut of an obese human to the guts of mice caused the mice to become obese. Since glyphosate induces a shift in gut bacteria towards endotoxin-producers, glyphosate exposure maycontribute to obesity in this way.

Reproductive problems: Studies of laboratory animals have found that male rats exposed to high levels of glyphosate, either during prenatal or pubertal development, suffer from reproductive problems, including delayed puberty, decreased sperm production, and decreased testosterone production.

Respiratory illnesses: House-to-house surveys of 65,000 people in farming communities in Argentina where Roundup is used, known there as the fumigated towns, found higher rates of chronic respiratory illnesses.
 
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