I ran a bottle of Lucas 4 years ago when I first got my truck. Truck ran pretty badly on the Lucas.
I use MMO in every fuel fill and part of the time in my oil. My engine runs quiet and very smooth, I get a small but noticeable power gain and I get about 1 to 2 more MPG with MMO than without. I also found MMO works better for me when I use good brand name gas. I used MMO on discount warehouse store gas, and did not see the better results that I had when I used name brand gas. My truck runs best on Chevron or Texaco. If they are not available I use Sunoco or Shell.
if you try MMO, give it 3 or 4 tanks to provide noticeable improvements. You may also need to experiment with the dose in the fuel. MMO recommends 4 ounces to 10 gallons of gas. For me, 2 to 2.5 ounces works best. 4 ounces actually hurt my gas mileage a bit.
YMMV. I personally don't care much for Lucas, but MMO is a great product.