I work on a lot of Hondas, not for a living, but enough to own an HDS unit with the ability to flash a PCM. The last one was a 2006 Pilot with VCM. 126,000 miles and in for a timing belt and full tune up. The owner was having random MIL events with multiple cylinder misfire codes stored. There is a TSB for at least 2006-2008 V6 equipped vehicles with VCM. This requires the valve lash to be adjusted and an update to the PCM. Otherwise this vehicle was neglected, but still runs well with even compression.
You didn't mention a year or model, but that is my most recent experience. I personally won't buy a lower mileage/new vehicle with VCM. If it's 100k+ with no history of VCM related mechanical problems, I just might be a buyer.
Some are good, and never have problems, and others are nothing but problems. I'm not sold on "Earth Dreams" yet either.