The issue with 2-stroke diesels is they require a low-ash oil. Particularly to prevent accumulation of deposits (ie: chunks of carbon) on the exhaust ports which, after a significant period of idling, have a tendency to migrate, upon application of load, to the turbocharger and cause FOD damage. Traditionally multi-grades required a lot of additives in order to achieve their 'multi-grade' status, hence, multi-grades were discouraged in such engines.
The bigger 2-stroke diesels (ie: EMD 710, EMD 645 with EFI kits, etc.) modified with EFI have moved to cylinder deactivation to combat this problem (ie: heavier loading on a lower number of cylinders causes a reduction in deposit formation, and thus, less likelihood of FOD-induced turbocharger failure).