daves66nova,
You generally don't need too much filtration in audio once past the front end stage. It's usually not a bad idea for digital sources, which are more sensitive to power irregularities, particuarly the modest-priced gear. It can also have minor benefit in some analog sources.
But once you get into the pre and power stages, a good internal PSU topology usually does a good filtration job. In a really high power system, you don't want much between you and the mains supply, other than transient protection.
Obviously, a cheap mass market audio instrument is not going to have as robust a power supply, and is generally capped and section supplied at marginal values throughout, so a spike/surge strip can be particularly helpful to them.
For most folks, something like an Isobar is enough for the typical system. Unless you've money to burn, solutions like a PS Audio power plant tend to be a poor value for most.
If you are looking to limit nominal mains voltage for some reason, a good variac is sometimes a good starting point to see if that is necessary.