FYI, a MERV-17 filter is a HEPA filter.
The box fan idea noted above is a well tested method of cleaning air. One experimenter used MERV-13 filters, a box fan and a small ionizer module. Matching HEPA filter performance easily.
The 5 sided square filter idea is how we filter incoming air for aircraft hangar AC. Lots of filter area, little restriction. Air handler dumps air directly into the hangar, no ducts.
Also note, some filter panels are MERV-11 or so, but have an electrostatic charge, greatly improving performance on small particles as long as the charge lasts (generally until the filter gets dirty)