I had Midas put synthetic in my 2006 RAV4 on a whim a couple of times around 2010 or so, I think they used Valvoline but I'm not sure. They told me that I could never go back to conventional after that, but even then I smelled a strong whiff of BeeEss on that one. I know that a statement like this opens me up to ridicule, but the RAV4 felt "slippery" to me after the first synthetic change...it's hard to explain exactly what I mean, but I have seen other people online use the same term for the sensation and it was the term that came to mind when I first started driving the car. It sounds insane and I can't explain it, but I went into it thinking that the oil might just last longer and was shocked to find myself thinking the car had a different feel...I almost wanted to have the stuff drained out at first.
My first DIY change, which was also my first with synthetic, was in 2014 with Mobil 1 5W30 in my '14 FXT.