2002 VW Jetta: Manual states to use 28 PSI in front and 26 PSI in rear. I filled all to 32 PSI. Ride quality went down, but the car handled better.
2003 Saturn ION: Manual stated 30 PSI in all tires, but handling and treadwear improved by using 34 in front and 32 in back.
1997 Lexus ES300: Manual stated to use 26 PSI on all 4 tires. Filling to 30 PSI made for ideal ride quality and treadwear.
2002 Toyota Solara: Manual stated that for 205/65/15 tires, use 29 PSI. I used 32 PSI, which is also the pressure recommended for 205/60/16 tires.
2005 Jeep Grand Cherokee: Manual states to use 33 PSI in all tires. I use 36.
2007 Pontiac G6: Manual states to use 30 PSI in all tires. Dad uses 32 PSI because it improves handling and fuel efficiency, but has little effect on ride.
On all other cars in my family, we simply did what the door sticker said, it usually said to use 32 PSI, so sometimes, we put that in cars that took less pressure, simply because we sometimes don't read the user manual or door sticker.
When I work on a car that belongs to someone who doesn't check their own pressure, I usually run 3-5 PSI above the door sticker. However, in large vans and trucks I run 35 PSI unless the door sticker says more. I do that because of all the short lived tires that happen when the car's manual states to use 26 PSI.