People sweat over the oil cooler seals failing in the OM642. So people have it done as "preventive maintenance" even though there is no leak. The oil cooler is a heat exchanger that shares coolant passages and oil passages. The material of the seals has been changed twice. It's a bad design with the oil cooler on the block and under the manifolds and all. Everything has to come off for it.
If the tech isn't meticulous, coolant and crud from the top of the block will get into the oil passages and it's quite common for that to cause spun bearings straight out of the shop. Of course, Mercedes and independent shops always say the engine was on it's last legs and it isn't their fault for putting coolant or crud into the oil passages.
My 2008 E320 Sedan has never had a leak in 165k miles and I would never consider doing a "preventive" change. If it ain't broke, don't fix it. Because you may fix it so it never works again.
OM642 engines that never had the seals changed don't spin bearings. Tens of thousands of these engines have run hundreds of thousands of miles in Sprinters and sedans with no problem. The SUVs and Sprinter owners who insist on running HDEO instead of the MB229.51/52 oils seam to be the ones that fail.