What are you going to be using this card for? If it's for storing of larger files (like audio/video media), then high speed cards would be good (Class 10, UHS I, etc.).
However, I've heard on here from someone (Panda?), that Class 2/4 cards are faster for random read/write on very small files, so depending on what you'll be storing/accessing from that card, that may be something to consider. But I'm not 100% sure this holds true for every Class 2/4 card out there.