I've used only E85 in all my gas vehicles for the past 6 years since it is 2 to 3x cheaper than gas here. A common practice is to replace the fuel filter one or two times during the first few thousand miles as the amount of crud removed from the fuel tank can be significant on older cars. Problems always have to do with poor ECU tunes or some stock ECUs not being able to ad enough fuel on non flexfuel/non converted cars. I've always wanted to know if valves/valve seats, cylinder liners, rings etc would wear out sooner but with the amount of high mileage cars running the stuff around me, and with non car people not doing anything different than they would with gas (OCI length, warm up time etc), i think it makes zero difference. Ethanol can attract water but on the other hand it produces almost no carbon deposits at all. About oil : I would run shorter OCIs than i would with gas if i did short trips but honestly, the only difference i ever noticed is that the only takes way longer to turn black, so who knows, maybe you can extend it with a good SN oil. There's a video somewhere on youtube where a guy from Blackstone explains that using E85 can in some cases result in a small drop in viscosity. I tend to avoid 5w30 and use a Xw40 now just to be extra safe.
