No, it's an entirely different formula. But it's still silicate/phosphate-free, which I personally prefer.
I doubt Amsoil's formulation is significantly different, anyway, as most extended-life coolants on the market today use very similar ingredients, though Amsoil uses PG instead of EG. The different "base" is really "irrelevant" as to the problems associated with DexCool, anyway.
I personally use Prestone All Makes All Models in the Saturn and it works perfectly fine. The previous fill was Prestone DexCool (red) for just over two years. The DexCool was cloudy and had a bunch of clumps in there, but I didn't install the DexCool, so I was unsure how the product was installed, which could've made all the difference in the world.
When I installed the yellow juice in the Saturn, I just drained the block and radiator, refilled with tap, ran it for 10 minutes, drained again, then refilled. To my surprise, the color has been perfect and I see no clumps of any kind in there. Only a slight strange odor that seems to be common with many coolants.