Allulose in my coffee and homemade keto desserts has a GLP1 effect too.
I'm a Lean Mass Hyper-Responder (LMHR) Now - You?
- Thread starter jetman
- Start date
Just checked my Blood glucose & ketones just now before going to bed, 95 and 2.3.
first time for ketones over 2.0 for me
first time for ketones over 2.0 for me
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@jetman
I did this quickly, call it a data dump in case you are interested. This is the last almost 10 years (to follow in next post) However throughout my life my numbers were always good, yeah, a slip up now and then with weight but nothing close to what happened to my weight last year do to the treatment and me living in some alternate universe.
For clarity, you already know my C-reactive protein was greater than 3 and Lipo A at 113 was tested in 2023
This year (2025) CAC score (my first ever) was a terrible 474 nothing can be done about it. Except TRY put a halt to the procession if I havent already. High Lipo A might make that impossible I dont know yet.
MANY Previous heart echos show excellent EF scores in the 55 to 60 range. Pervious cardiac angiogram shows blockages all over the place of only 20% which is really good considering the above. Firmly believe I would be in WAY, way worse shape if not always reasonably watching what I eat. Though now I am taking it to a more extreme level.
Also this year my first ever fasting insulin came in a less than flattering 11
...
and finally found out I have been skirting fasting higher blood sugar at times but nothing alarming until Nov 2025 at 123 most likely due to a combination of factors. Current 2 hour glucose last week shows "pre diabetic" Yet A1C of 5.6 in Dec was only 5.3 in Jan, firmly believe do to new way of eating, losing weight and working out of an immense amount of steroids I was given Oct and Nov 2025
SO this is my year to do everything humanly possible, I have learned a lot so far reading and reading yours and others experiences.
Data in next post.
I did this quickly, call it a data dump in case you are interested. This is the last almost 10 years (to follow in next post) However throughout my life my numbers were always good, yeah, a slip up now and then with weight but nothing close to what happened to my weight last year do to the treatment and me living in some alternate universe.
For clarity, you already know my C-reactive protein was greater than 3 and Lipo A at 113 was tested in 2023
This year (2025) CAC score (my first ever) was a terrible 474 nothing can be done about it. Except TRY put a halt to the procession if I havent already. High Lipo A might make that impossible I dont know yet.
MANY Previous heart echos show excellent EF scores in the 55 to 60 range. Pervious cardiac angiogram shows blockages all over the place of only 20% which is really good considering the above. Firmly believe I would be in WAY, way worse shape if not always reasonably watching what I eat. Though now I am taking it to a more extreme level.
Also this year my first ever fasting insulin came in a less than flattering 11
...
and finally found out I have been skirting fasting higher blood sugar at times but nothing alarming until Nov 2025 at 123 most likely due to a combination of factors. Current 2 hour glucose last week shows "pre diabetic" Yet A1C of 5.6 in Dec was only 5.3 in Jan, firmly believe do to new way of eating, losing weight and working out of an immense amount of steroids I was given Oct and Nov 2025
SO this is my year to do everything humanly possible, I have learned a lot so far reading and reading yours and others experiences.
Data in next post.
@jetman
For some reason when I download my data it is not including 2017 which I post right below
[th]
[/th]
From 2018 to current
Anyway, these are all pretty respectable numbers yet have a CAC score of 471 and 20% + plaque "all over the place" in my arteries. In addition to no diabetes. Someone would have to believe there is something genetic going on like the High Lipo A that I have.
For some reason when I download my data it is not including 2017 which I post right below
[th]
[/th]
From 2018 to current
Anyway, these are all pretty respectable numbers yet have a CAC score of 471 and 20% + plaque "all over the place" in my arteries. In addition to no diabetes. Someone would have to believe there is something genetic going on like the High Lipo A that I have.
PS, I just saw in 2017 I had an A1c of 5.0 and BG below normal at 67 (on my chart is says "abnormal" *LOL*)
I probably missed it in my ADHD, but those numbers look like statins involved. Statins and when, if so?
GOOD POINT!
Thank god I have now been in the APPLE world for many years or I would have been widely guessing but even so I would have been pretty accurate because it is the first and only real daily medication I ever had to take other than a daily aspirin. It's still that way to this date.
Anyway, thanks to my Apple calendar I just went back and looked.
Feb 23 2021 I had a Cardiac Catherization done. Follow up on March 10th 2021 I was prescribed a Min Dose 5mg statin. Being my Lipids were so good I questioned it, They explained its a min dose and based on my results it should be looked at as a preventive medication for the "rest of my life" as it has other benefits for the arteries and veins (something like that)
So anyway, my first daily medication in my life (other than my aspirin) was that statin, still remember clear as day.
So safe to say, 5mg statin started the week of March 15th 2021
Actually looking at my chart I can see the drop in June 2021!
Thanks for that post!
Here's a video with preventative cardiologist Matthew Budoff talking about the Keto Trial study on LMHR:
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Here's the clinical trial study that was done on a LMHR group:
https://clinicaltrials.gov/study/NCT05733325?tab=study#study-overview
https://clinicaltrials.gov/study/NCT05733325?tab=study#study-overview
Here's what been happening with me since I reduced my dietary carbs 18 mths ago:
Yeah the altitude always gets people
Cholesterol #s can be high for those that are lean and on a low carb diet, < 20 gr/day.
According to Dr. Ken Berry:
1/3rd of low carb eaters have their LDL #s go down
1/3rd their LDL goes up
1/3rd their LDL stays about the same
AND 1% become a LMHR
My lab #s show that I became one of the 1%, a LMHR, sometime between Oct. 2025 & Feb. 2026. That aligns perfectly with when I cut my carbs from roughly 75 grams/day to <20 grams/day. I haven't lost any additional wt since I went <20 gr/day. But I did lose 50 lbs (208 to 158) in the 15 mths beforehand on Paleo/low carb intake.
Generally, LMHR have the following lipid #s:
LDL of 200 mg/dL (5.17 mmol/L) or higher, my latest = 234 mg/dL, 1 yr ago = 151
HDL of 80 mg/dL (2.07 mmol/L) or higher, my latest = 89 mg/dL, 1 yr ago = 58
Triglycerides of 70 mg/dL (0.79 mmol/L) or lower, my latest = 69 mg/dL, 1 yr ago = 100
LMHR are also lean, < 20% body fat, and athletic.
They are metabolically healthy too, which I am.
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Also pay attention to your ALT. Paints a similar picture to triglycerides. Note the typical published ranges for acceptable ALT are garbage.
You lost 40 pounds. What are your further goals?
You lost 40 pounds. What are your further goals?
My lALT result from last week was 19, in a range of 5 to 55.
I've lost 50 Lbs (208 to 158). I weigh what I did my sophomore yr in HS
I lost all this weight slowly (15 mths), before I went super low carb and into ketosis.
@Pablo
Plaque Begets Plaque, and since I know I have CVD = CardioVascular Decease = NOT Good
I'm 68 yrs old, BMI=22, <20% body fat, 5'11", 158 Lbs, eating low carb/high fat ketogenic diet. I have been fat adapted and in a mild state of nutritional ketosis since last Dec. I'm athletic & metabolically healthy.
I'm a Lean Mass Hyper Responder (LMHR). I have no other health issue(s) that I know of.
IMO my heart attack/stroke risk is elevated.
How/Why do I think this?
I have heart artery calcified stable plaque as determined by my CAC test I had done 4 of 2025,
and
I have carotid artery heterogeneous partially calcified plaque in both left & right sides as determined by my CIMT scan test I had done 2 weeks ago.
April 2025, for curiosity sake, I had a CAC score test (Coronary Artery Calcium) done = 33 Agaston score in my LAD (Left Anterior Descending = widow maker) artery. 11-100 is considered a "MILD" risk of CAD = coronary artery decease. They gave me an arterial age of 65. I was 67.
Then a couple of mths ago after I saw/read the Keto CTA study which states "Plaque Begets Plaque" I did a little more research and discovered the non-evasive Carotid Intima Media Thickness/CIMT test by CardioRisk. My CIMT results could have been better but could have been worse. My left & right carotid bulbs and the left CCA have heterogeneous = partially calcified plaque, which is somewhat stable and less risky than soft plaque. They gave me an arterial age of 80. I'm 68.
This week I had my medicare annual wellness tests/visit with my primary care physician (PCP). He was concerned about my high LDL. I asked if he knew what a Lean Mass Hyper Responder was. He did not. So I didn't mention my CIMT test results. I did tell him I was concerned too and asked for him to order a medicare approved imaging test that can see soft caronary artery plaque. So he ordered a CT Angiogram (with contrast) on my Coronary Arteries with Fractional Flow Reserve. Its schedued for April 15th. We will see.
In the meantime I'm not changing a thing until after I get my April 15th test result.
I feel great! That's often the thing. You feel great until you don't.
Plaque Begets Plaque, and since I know I have CVD = CardioVascular Decease = NOT Good
I'm 68 yrs old, BMI=22, <20% body fat, 5'11", 158 Lbs, eating low carb/high fat ketogenic diet. I have been fat adapted and in a mild state of nutritional ketosis since last Dec. I'm athletic & metabolically healthy.
I'm a Lean Mass Hyper Responder (LMHR). I have no other health issue(s) that I know of.
IMO my heart attack/stroke risk is elevated.
How/Why do I think this?
I have heart artery calcified stable plaque as determined by my CAC test I had done 4 of 2025,
and
I have carotid artery heterogeneous partially calcified plaque in both left & right sides as determined by my CIMT scan test I had done 2 weeks ago.
April 2025, for curiosity sake, I had a CAC score test (Coronary Artery Calcium) done = 33 Agaston score in my LAD (Left Anterior Descending = widow maker) artery. 11-100 is considered a "MILD" risk of CAD = coronary artery decease. They gave me an arterial age of 65. I was 67.
Then a couple of mths ago after I saw/read the Keto CTA study which states "Plaque Begets Plaque" I did a little more research and discovered the non-evasive Carotid Intima Media Thickness/CIMT test by CardioRisk. My CIMT results could have been better but could have been worse. My left & right carotid bulbs and the left CCA have heterogeneous = partially calcified plaque, which is somewhat stable and less risky than soft plaque. They gave me an arterial age of 80. I'm 68.
This week I had my medicare annual wellness tests/visit with my primary care physician (PCP). He was concerned about my high LDL. I asked if he knew what a Lean Mass Hyper Responder was. He did not. So I didn't mention my CIMT test results. I did tell him I was concerned too and asked for him to order a medicare approved imaging test that can see soft caronary artery plaque. So he ordered a CT Angiogram (with contrast) on my Coronary Arteries with Fractional Flow Reserve. Its schedued for April 15th. We will see.
In the meantime I'm not changing a thing until after I get my April 15th test result.
I feel great! That's often the thing. You feel great until you don't.
Our numbers are not hugely different, but I still say I'm missing something. My insulin response is weak and slow. I don't know exactly why.@Pablo
Plaque Begets Plaque, and since I know I have CVD = CardioVascular Decease = NOT Good
I'm 68 yrs old, BMI=22, <20% body fat, 5'11", 158 Lbs, eating low carb/high fat ketogenic diet. I have been fat adapted and in a mild state of nutritional ketosis since last Dec. I'm athletic & metabolically healthy.
I'm a Lean Mass Hyper Responder (LMHR). I have no other health issue(s) that I know of.
IMO my heart attack/stroke risk is elevated.
How/Why do I think this?
I have heart artery calcified stable plaque as determined by my CAC test I had done 4 of 2025,
and
I have carotid artery heterogeneous partially calcified plaque in both left & right sides as determined by my CIMT scan test I had done 2 weeks ago.
April 2025, for curiosity sake, I had a CAC score test (Coronary Artery Calcium) done = 33 Agaston score in my LAD (Left Anterior Descending = widow maker) artery. 11-100 is considered a "MILD" risk of CAD = coronary artery decease. They gave me an arterial age of 65. I was 67.
Then a couple of mths ago after I saw/read the Keto CTA study which states "Plaque Begets Plaque" I did a little more research and discovered the non-evasive Carotid Intima Media Thickness/CIMT test by CardioRisk. My CIMT results could have been better but could have been worse. My left & right carotid bulbs and the left CCA have heterogeneous = partially calcified plaque, which is somewhat stable and less risky than soft plaque. They gave me an arterial age of 80. I'm 68.
This week I had my medicare annual wellness tests/visit with my primary care physician (PCP). He was concerned about my high LDL. I asked if he knew what a Lean Mass Hyper Responder was. He did not. So I didn't mention my CIMT test results. I did tell him I was concerned too and asked for him to order a medicare approved imaging test that can see soft caronary artery plaque. So he ordered a CT Angiogram (with contrast) on my Coronary Arteries with Fractional Flow Reserve. Its schedued for April 15th. We will see.
In the meantime I'm not changing a thing until after I get my April 15th test result.
I feel great! That's often the thing. You feel great until you don't.
My ALT is 20.
I only wish I had your scores@Pablo
Plaque Begets Plaque, and since I know I have CVD = CardioVascular Decease = NOT Good
I'm 68 yrs old, BMI=22, <20% body fat, 5'11", 158 Lbs, eating low carb/high fat ketogenic diet. I have been fat adapted and in a mild state of nutritional ketosis since last Dec. I'm athletic & metabolically healthy.
I'm a Lean Mass Hyper Responder (LMHR). I have no other health issue(s) that I know of.
IMO my heart attack/stroke risk is elevated.
How/Why do I think this?
I have heart artery calcified stable plaque as determined by my CAC test I had done 4 of 2025,
and
I have carotid artery heterogeneous partially calcified plaque in both left & right sides as determined by my CIMT scan test I had done 2 weeks ago.
April 2025, for curiosity sake, I had a CAC score test (Coronary Artery Calcium) done = 33 Agaston score in my LAD (Left Anterior Descending = widow maker) artery. 11-100 is considered a "MILD" risk of CAD = coronary artery decease. They gave me an arterial age of 65. I was 67.
Then a couple of mths ago after I saw/read the Keto CTA study which states "Plaque Begets Plaque" I did a little more research and discovered the non-evasive Carotid Intima Media Thickness/CIMT test by CardioRisk. My CIMT results could have been better but could have been worse. My left & right carotid bulbs and the left CCA have heterogeneous = partially calcified plaque, which is somewhat stable and less risky than soft plaque. They gave me an arterial age of 80. I'm 68.
This week I had my medicare annual wellness tests/visit with my primary care physician (PCP). He was concerned about my high LDL. I asked if he knew what a Lean Mass Hyper Responder was. He did not. So I didn't mention my CIMT test results. I did tell him I was concerned too and asked for him to order a medicare approved imaging test that can see soft caronary artery plaque. So he ordered a CT Angiogram (with contrast) on my Coronary Arteries with Fractional Flow Reserve. Its schedued for April 15th. We will see.
....
Im sure you know CAC scores
Source https://my.clevelandclinic.org/health/diagnostics/16824-calcium-score-screening-heart-scan
I already knew I had CVD from an angiogram/angioplasty
Then on my own a CAC which will make it easy to compare in coming years
My CAC score was 477
Since I have the documentation now, it's my hope that my cardiologist will order a CIMT on my behalf if the ins company will pay, I think they will because of my history.
Where did I get my plaque?@Pablo
Plaque Begets Plaque, and since I know I have CVD = CardioVascular Decease = NOT Good
I'm 68 yrs old, BMI=22, <20% body fat, 5'11", 158 Lbs, eating low carb/high fat ketogenic diet. I have been fat adapted and in a mild state of nutritional ketosis since last Dec. I'm athletic & metabolically healthy.
I'm a Lean Mass Hyper Responder (LMHR). I have no other health issue(s) that I know of.
IMO my heart attack/stroke risk is elevated.
How/Why do I think this?
I have heart artery calcified stable plaque as determined by my CAC test I had done 4 of 2025,
and
I have carotid artery heterogeneous partially calcified plaque in both left & right sides as determined by my CIMT scan test I had done 2 weeks ago.
April 2025, for curiosity sake, I had a CAC score test (Coronary Artery Calcium) done = 33 Agaston score in my LAD (Left Anterior Descending = widow maker) artery. 11-100 is considered a "MILD" risk of CAD = coronary artery decease. They gave me an arterial age of 65. I was 67.
Then a couple of mths ago after I saw/read the Keto CTA study which states "Plaque Begets Plaque" I did a little more research and discovered the non-evasive Carotid Intima Media Thickness/CIMT test by CardioRisk. My CIMT results could have been better but could have been worse. My left & right carotid bulbs and the left CCA have heterogeneous = partially calcified plaque, which is somewhat stable and less risky than soft plaque. They gave me an arterial age of 80. I'm 68.
This week I had my medicare annual wellness tests/visit with my primary care physician (PCP). He was concerned about my high LDL. I asked if he knew what a Lean Mass Hyper Responder was. He did not. So I didn't mention my CIMT test results. I did tell him I was concerned too and asked for him to order a medicare approved imaging test that can see soft caronary artery plaque. So he ordered a CT Angiogram (with contrast) on my Coronary Arteries with Fractional Flow Reserve. Its schedued for April 15th. We will see.
In the meantime I'm not changing a thing until after I get my April 15th test result.
I feel great! That's often the thing. You feel great until you don't.
Probably from 20+ yrs (1974ish to 1995) of chewing/dipping Copenhagen tobacco. I was young a bullet proof then. NOT NO MOE.
What is the mechanism here? Chew=>plaque
large amounts, yrs & yrs, of addictive Nicotine = plaque