On a 2006 Honda Accord
with factory fill , ,under the worst possible conditions , short of contaminating your system 7.5YR/100K.
You want to do something to feel good , 5YR/60K
GA 05 on this one , nope , never . HONDA T2 and that engine/radiator are extremely well matched . Honda T2 is also well made .
Want to do something really useful to help your cooling ?
Correctly clean your radiator's exterior twice a year , with one being done after spring has arrived .
If you just really , really , gotta do something to your cooling system , wait until you are out of your warranty , comeback here , see what Gary Allen and others like him are doing here with cooling system filtration , and then do something .
Something you could do now for your cooling system and this no joke , nor meant with any disrespect , is get a seriously accurate tire gauge , learn how to use it correctly , and then use it .
If you want something to " overmaintain " of great benefit , do your atf ( if so equiped ) and start early ( 4 - 5K ).
Stay with Honda's ATF - Z1 during warranty .
I'm saying all this with MA. , your wallet , and your 06 Accord in mind.