Yes, I've been through a few of each. All of these had lots of highway & mountain miles and were dealer maintained while under warranty.
'84 Toyota LE Van, OEM transmission stopped shifting at ~80K - traded in after Mr. Transmision rebuild that never worked properly.
'87 Ford Aerostar, 1st transmission under warranty ~30K miles, 2nd at AAMCO ~70K, 3rd @AAMCO ~140, failed at 190K and scrapped.
Head gasket at ~60K
'91 Aerostar, 1st transmission @ ~ 80K miles, otherwise pretty reliable. Engine let go at ~190K scrapped.
'95 Chevy 1500 conversion van, multiple transmissions under warranty, after warranty an indie put in a heavier duty equivalent, never broke again. Given to a friend with ~250K
'04 Audi A4, first CVT ~13K, 2nd CVT ~43K, lots of other issues, traded at 67K.
Since then, we have had multiple vehicles that have gone over 200K w/o engine or transmission issues.