If you look at a VOA of Mobil 1 20-50 Vtwin or 10-40 ( both JASO spec ) they do have moly but no friction modifiers. Same if you look at a diesel 15-40 it has moly and this particular oil is recommended by HD if you are caught in a pinch and can't get the oil that they recommend for any of the 3 holes, which is a dino 20-50. Twin cam engines 88, 96, and up.
There is nothing unique about a HD engine, primary or transmission ( other than having roller bearings ) that precludes one from using just about any oil as long as it is in the right weight for the ambient temps. The HD primary is really no different than motorcycles with shared sumps, you have to stay away with friction modifiers because of the wet clutch. There is nothing in the HD engine or transmission that would preclude somebody from using an oil with friction modifiers as long as the weight was proper for the ambient temps.
On a BMW motorcycle site I follow, I recently saw a set of virgin VOA's from about 10 different 20-50's ( for motorcycle use ), one 15-50, a couple of Amsoil products and a 15-40 diesel oil, Harleys 20-50 dino, some dino & some sync. The zinc & phosphorus levels varied between the various oils but all of them exceeded the 1200 ppm zinc levels that BMW recommended for its air cooled flat tappet engines. HD is also a flat tappet engine, with roller bearings instead of the plain bearings found in an air cooled BMW motorcycle.
So in a nutshell any of the oils tested would work fine in any air cooled flat tappet engine, which a HD is. The SN version of Castrol Syntec 5-50 has 1300 PPM of zinc.