I'm sure that you have seen splatter on the wheels of trailers. That splatter is usually grease that has leaked from the hub. When grease reaches its dropping point and liquefies, it can get through the seals and leak away. The same thing can happen to grease in various motors. As they heat up, the grease liquefies and leaks through the seals.
There are a number of reasons for grease loss depending on use. Another one would be grease used in boat trailers that do in and out of water a lot. They suffer from washout.
Finding the right grease for each application requires proper research. Personally, I tend to go with a higher grade of product than typically recommended as it will usually result in less maintenance time and less repair costs down the road.
Spending a little more on a higher quality grease most definitely pays off in the long run. But be aware of incompatibility issues, and other issues based on what is in the grease.
An example that I am aware of comes from South Africa where a company is using a lot of heavy equipment in a wet environment. The recommended grease also has 5% moly in it due to the EP needs. They have been experiencing corrosion that they believe is grease based as when molybdenum disulfide when mixed with water creates sulfuric acid. Over a longer period, that can cause pitting and corrosion in the metal.