Always remember that an engine needs four things to run: Spark, fuel, compression, and timing.
The first two are easiest to check.
Replace the plug - they're cheap. Check that there is a spark by removing the plug, holding on to it, and pulling the starter cord briskly. Or, if you don't like the feeling of being electrocuted, ground the plug against the cylinder, pull the cord, and observe for a bright blue spark. If you have a new plug, there could be a problem with the electronic ignition module.
Check the NEW fuel line to make sure it is on snug, not pinched, or damaged during install. Pull the cord with a DRY plug installed, remove the plug, and look for signs of gas (wetness). If dry, it might be a carb problem or fuel line problem.
The compression and timing will be covered in the next class.
I have also seen many people run 2 cycles too long at less than full throttle and carbon up the muffler screen enough to keep the engine from running. Remove the muffler and clean the internal screen and ports.
Good luck!