I have used Tufoil for a long time; with 1-5% PTFE by weight, I haven't experienced any issues. I started using it in the late 1980s due to the fact that in Omaha, the engine on my Honda Accord would make a loud noise on really cold days. After putting in Tufoil, the noise went away. In our Lexus RX330, the used oil analysis have come back with no concerns (just additional moly). I put 4 oz in at each oil change, change the oil every 5,000 miles and the filter (Fram Ultra or OEM) every 10,000 miles. Lexus makes such a bullet-proof engine, I would never say Tufoil is a miracle additive, but from my experience, it doesn't hurt. As always, YMMV.