Most of the members here feel additives are redundant or sometimes even harmful. This one sounds redundant to me, so why add an incremental cost per quart to an oil change?
Motor oil, especially a synthetic, can already do what Power Up does (as per the web page):
1. Strong film affinity maintains lubrication at start-up
2. By reducing the generation of large wear particles, the efficiency of the oil filter is improved
3. High base number helps neutralize acids that cause corrosion.
4. Reduces friction and metal to metal contact in high load areas of the engine
5. Reduces friction and lowers temperatures in critical bearing and ring zones
6. Has a powerful detergent which cleans and suspends sludge and varnish
But if you want to do a test, keep track of any gas mileage improvements, do an oil analysis before and after treatment, and report back.