On December 19, 2005, the EPA removed methyl ethyl ketone (MEK, or 2-butanone) from the Hazardous Air Pollutants List of the Clean Air Act.
The Ketones Panel of the American Chemistry Council had submitted a petition which stated "emissions, ambient concentrations, bioaccumulation, or deposition may not reasonably be anticipated to cause adverse effects to human health or adverse environmental effects."
So it would seem that at concentrations that are not ridiculously high, MEK is not mutagenic or genotoxic.
The Ketones Panel of the American Chemistry Council had submitted a petition which stated "emissions, ambient concentrations, bioaccumulation, or deposition may not reasonably be anticipated to cause adverse effects to human health or adverse environmental effects."
So it would seem that at concentrations that are not ridiculously high, MEK is not mutagenic or genotoxic.