I'm a Lean Mass Hyper-Responder (LMHR) Now - You?

I found you get better responses if you can claim a symptom that warrants a test. It gives the doc something to put in your chart to get it approved.
Agree, I got a few, family history, my history of past angiogram )5years)showing plaque all over the place 20 to under 30% blockage, Jan 2026 cac score = 474 (also noted arterial plaque in annual lung scan most recent Dec 2025

My PSMA pet scan for PSMA cancer in Dec 2024 noted calcium in the prostate

HOWEVER the clincher will be my compliant about chest pressure over the Memorial Day weekend, thought about going to the ER, most likely stupid that I didn’t and still played pickleball.

I’m most likely overly concerned about not getting one but leaving nothing to chance. Memorial Day weekend was kind of scary. Felt like I had a hand on my chest pushing down gently

Jetman got his without issue, hope I have the same if not another Dr I feel they are not reading my tests vs just summaries
 
Genetics definitely plays a part of this

Genetics? It does play a role
but so does lifestyle.

My family history = lifestyle choices, not genetics

My mom, died from a stroke in her 70s because she didn't eat right, drank too much, and didn't exercise the last many yrs of her life. She smoked until her late 60s, survived lung cancer with early diagnosis and surgical removal of 2 of the 3 lobes from 1 of her lungs. No chemo but did have some radiation treatment.

My dad, died in his 70s, never woke up from heart surgery (AFIB etc), didn't eat right, drank too much, and didn't exercise the last 40 yrs of his life.

2 of my 4 grandparents died from heart attacks. one was 55ish yrs old, and the other was 65ish yrs old. Both smokers.

I made bad lifestyle choices from 1974 to 1995. I dipped snuff (copenhagen chewing tobacco) and abused alcohol (beer). Gave up both in 1995, 31 yrs ago, but the damage was done. Young, dumb, and bullet proof.

OH, and I thought I was eating healthy = low fat/high carb. 21 mths ago I discovered I'd been lied to.

NOT!
 
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Genetics? It does play a role
but so does lifestyle.

My family history = lifestyle choices, not genetics

My mom, died from a stroke in her 70s because she didn't eat right, drank too much, and didn't exercise the last many yrs of her life. She smoked until her late 60s, survived lung cancer with early diagnosis and surgical removal of 2 of the 3 lobes from 1 of her lungs. No chemo but did have some radiation treatment.

My dad, died in his 70s, never woke up from heart surgery (AFIB etc), didn't eat right, drank too much, and didn't exercise the last 40 yrs of his life.

2 of my 4 grandparents died from heart attacks. one was 55ish yrs old, and the other was 65ish yrs old. Both smokers.

I made bad lifestyle choices from 1974 to 1995. I dipped snuff (copenhagen chewing tobacco) and abused alcohol (beer). Gave up both in 1995, 31 yrs ago, but the damage was done. Young, dumb, and bullet proof.

OH, and I thought I was eating healthy = low fat/high carb. 21 mths ago I discovered I'd been lied to.

NOT!
Agree,
My dad died of a heart attack close to 30 years ago, diabetes, quad bypass. HE was overweight but tried not too. Not obese like I see in today's world by any means. Big guy, just over 6 feet. Back then everyone (almost) smoked, high pressure (sort of) job with a well known newspaper, he did well. Thing is, back then, foods were wholesome, and we didnt sit around eating snacks all night. Stay at home mom always cooked homemade meals. He did quit smoking (guessing) in his early 40s. Once I (we started) learning in elementary school that smoking is bad, seeing nasty movies of what happens to your lungs.

Brother, who used to preach to my dad about a better lifestyle was far worse and continues some of that today as far as food choices. HE too quit smoking around his 40s, no longer drinks. 6 years older than me now. Quad bypass decades ago, diabetes, currently as EF around 25. (yes that is correct) besides the bypass, to this day other procedures to correct/stabilize heart rhythm ... to this day still eats whatever he wants, never made an attempt to change diet. Says he lives for today and most of it is baloney. Oh well. You can see where that is going and has gone. Part that frustrates me is he used to make fun of me for not "living" in the way I ate. I got one acknowledgment of that 5 years ago when my invasive angiogram showed low levels of plaque all over the place but no intervention was needed.

Me? the only male in my family that looked to eat correctly, almost my entire life after learning what my dad went through and my brother later in life. Also used to smoke but around the time my first child was born in the late 80s I swore they would never see me smoke, for years before that my wife never saw me smoke. But I used to smoke at work. I stopped that. As far as health and weight, some years a bit more heavy than others but always within 10lbs of my BMI on the "trim" side always and much more muscular than I am now. I swore I would not end up like them, learned to also eat lean meats, a LOT of fruit even in the 1980s before that time, like any young unmarried guy, it was partying, drinking, smoking, eating anything that tasted good. Yeah, I get it, starting around 1974 to the 1980s at some point I was realizing that proper foods were important. We used to party almost every night after work with our friends, that stopped when my daughter was born. Yeah, I get the carbs thing, however just recently learned how bad they are. I still have an unopened box of shredded wheat in my pantry come to think of it!

SO where am I going with this other than circles? *LOL*
My mom's side of the family. Italian, her parents came right off the boat to the USA before she and her parents large family was born. Lots of carbs, wholesome though, my grandmother made EVERYTHING from scratch. Tons of pasta and all kinds of Italian dishes. Very close knit on my moms side, as our family was more than my dads side. Off the top of my head, 6 brothers and sisters. Not one of them had a heart procedure or diabetes. Best I remember all lived long lives in general, no young deaths. GO figure.
There was one or two, I am told that did get prostate cancer. But I had my genes tested and I didnt carry the gene.

My grandfather would swear the 2 glasses of red sweet wine he had at dinner was a cure all. He also bragged about having one cavity in a tooth his whole life because at the end of a meal he would swish the wine around his mouth. (got me*LOL*) Maybe the mind is more powerful than we think.

Ok, so me? I have hi- lipo (a) known to be hereditary and heart disease in the family is undisputed as a significant risk factor. Even more so, immediate family, father siblings. Heck it must be true if the medical "complex" even recognizes it in getting certain procedures approved as well as most the Dr videos we watch. SO you, like me, we dont know if we could have beat it or not. But maybe so or at least delayed it. For me, I have delayed it for sure, but it's there and why I want to know exactly where I stand with a scan.

Genes - another example, my wife came here at the age of 22 many decades ago from the Philippines. The family and family circle would be considered wealthy and even by US standards many very wealthy. However they (as you and I would see it) eat anything they want, without regards to fatty foods or carbs (as in rice) because of me, my wife eats better but she will still for example eat the nicely grilled fat in a T-bone steak where I trim off every little piece and put it in a bowl on the side. She would even eat that if I let her!
Growing up, the entire family would fight over the legs and thighs of a chicken vs who would get stuck with the breast meat.
Rice, OMG, she eats way too much, however has cut back a lot, and is aware, she is pre-diabetic but she will still have a portion.
She has never smoked or drank.
Ok, so genes - well now into her 60s, as I posted, at my insistence since her Apple Watch indicated she had hypertension. She saw a cardiologist. Now takes a lower dose high BP pill a day and in the normal range. Her family history is one of high BP. Not one has had a heart issue in the entire large family circle. IN fact her mom well into her 90s now is 100% still here mentally. Uses her iPad all day long and FaceTime's with her kids here in the USA, also uses Viber sending and receiving photos. As I posted, the kicker is, I had my wife do a CAC scan just a couple weeks ago score was = 0
 
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Oops, back to genes, I was looking at the link @Pablo posted.
From what I remember, my dad too. His lipid numbers were always good but the HDL like mine are low. Im always borderline low matter what I do, I cant get it higher. SO it's just high enough. But half of you. Im HDL 41 and no matter what I do have never been from what I remember 50 or above.
I know I dont do what you do to get those numbers, but still at this point ... just rambling on. My wife is always higher and my mom was aways higher along with her lipids in general were at face value worse than my dads with alll the heart problems he had. So I am a believer that there is way more to this whole lipid thing which we know now is true. The problem is once you have the arterial disease, lowering them as low as possible might be smart? I have no clue. All I know is I am still standing, against what I see as all odds.

This is with a 5mg rosuvastatin - lipids two weeks ago, already posted somewhere in my insanely long posts. I seriously am thinking after I get to meet with my cardiologist whom I still have to set an appt of going to 10mg, even if it takes my total a little below 100. I was to start 10mg last year, actually I have a bottle of them but I told him to hold off and let me see what I can do with diet so he reordered the 5mg.. Well I did it but ... he would like to see me with an LDL of closer to 20. Maybe in my case that isnt bad being my HDL is half of what @jetman is. Got me... oh, I am the only family member who knows what his Lipo (a) is = 116.5 So I cant compare that.

One thing he did tell me, is when you bump up a statin you have been taking a while, the resulting reduction is not as great as if you are starting off with that higher dose. I think he is pretty knowledgeable maybe I am biased knowing he interned at the Cleveland Clinic. Plus he was the only Dr who ever checked my Lipo(a) and C-reactive protein. I guess, I will see what I think of him this time around with all I have learned, plus the information posted in here. :) with the videos and books I read.
Screenshot 2026-05-29 at 8.36.00 AM.webp

HDL
 
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@jetman
I corrected the above to read "being my HDL" is half of yours. With you near 100 that makes your LDL not look as bad face value.
Edit - oh I do see your big jump in 2026 compared to that amazing ratio you had in 2025
BTW- Im just talking, you guys know more than me with much of this stuff. I only know the "me" part>
 
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@jetman
I corrected the above to read "being my HDL" is half of yours. With you near 100 that makes your LDL not look as bad face value.
Edit - oh I do see your big jump in 2026 compared to that amazing ratio you had in 2025
BTW- Im just talking, you guys know more than me with much of this stuff. I only know the "me" part>
Here's a Nick Norwitz video about Low Cholesterol I found interesting, especially chapter 5 "The Not Low Enough Trap":
 
Here's a Nick Norwitz video about Low Cholesterol I found interesting, especially chapter 5 "The Not Low Enough Trap":

I didnt even know that high LDL can be a direct cause in 12% but guess that makes sense.

I not a subscriber to having high LDL causes heart disease but seems reasonable to me in 12%.
BY far and large what we stuff in our mouths and inhale in our lungs are far worse. Metabolically our entire population with a percentage like even some in here is an exclusion is completely irresponsible in the crap 90% of us we stick in our mouth.
My feeling true cause of world wide heart disease (other than genetics) is what we eat, inflammation. If you want to significantly reduce heart disease we would outlaw most of the chemicals in our food, heck, eliminate all fast food, all refined carbs, all ultra processed foods. It's freaking stupid but it will never happen, too much money in the junk food products, too much money in the medical industry. Can you imagine if everyone ate responsibly in a nation where I would be over 90% do not?

Genetics is a major factor to overcome. He (and like all doctors like him) do not deny statins are evil for those with arterial disease. I never heard a doctor say otherwise but sometimes you REALLY have to listen to what they are saying. I do agree we are too focused on lipids. Im surprised he is good with A1C OF LESS THAN 5.5. I would like to be below 5. My fasting insulin is too high 11 ( I said this before even though some Drs think that is ok) I would start with his recommendations and would like to be at the low end as a goal.

With that said, statins which cost pennies and are all generic products I dont see as the big Pharma golden goose when he speaks about the 10 billion dollars to those big companies. What I see is a lazy population that doctors know 90% of us wont take our health serious and make the changes needed will prescribe a statin because they do alter the outcome for some but YES, its too focused on that and not on diet but we are lazy creatures when it comes to eating right.

All in all, I agree 100% with him, great video, thanks for posting. It's good to see these things from time to time. I find them, for me personally very motivating. So here is my deal, just last week (posted someplace here) met with my cardiologist ANP not happy about not seeing him personally that is the state of too little doctors. More so because I was wondering if I had an heart attack Memorial Day. Best they could do was make me wait two weeks and I got an ANP/ BTW- if following me, I have an appt July 8th with a new medical practice new cardiologist to feel out as a new patient, if I like what I hear I will switch networks. I want a proactive Dr. My current one is pretty good but ...

Meantime the ANP is ordering a stress/echo combination test that I will have to drive just over an hour to get and the network can not do a combo test and he wants it done for a reason that I zoned out by that part of the appt as it was a long appt.

Back to the video, yeah, if you were dealt a bad card like the ANP told me you cant overcome the genetics BUT you can mitigate them as much as possible. Since I know my veins and arterial walls are diseased and can be penetrated by LDL and Lipo (a) a super great diet and lowest possible lipids numbers will help stabilize the condition. He already complimented me as my numbers are stupid low. I mean my total is only 107 and LDL I was disappointed at 57 or 59 he thought was still ok with under 55 best. Yet my regular Cleveland Clinic dr not the ANP suggested studies as low as 20 help. But I'll never be able to get there.

So I COULD be living proof that by not eating and living like my dad did before he died at age 69 and my brother who is around 75 but quad by-passes, both horrible EF scores and both diabetes. My lipid levels far, far better than they ever were, my eating far, far better than they ever were has got me to the point of not diabetic yet (but by my measurement 2 hour glucose I am pre, not by A1C though) and no heart by passes and no heart attacks and as of late last summer cardiac echo that was literally perfect with an EF in the 58 to 60 range... yet I have plaque all over the place and VERY significant heart disease. I might be the example of why keeping LDL and lipid in general as low as possible has worked for me. As the ANP and my regular cardiologist has said, at least I am controlling the things I can control is helping me prevent complete blockages as I am unable to control the genetics
 
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